/* Base styles and custom CSS for Site360 Clinical Trial Platform */

/* Custom scrollbar for better UX */
::-webkit-scrollbar {
    width: 8px;
}

::-webkit-scrollbar-track {
    background: #f1f5f9;
}

::-webkit-scrollbar-thumb {
    background: #cbd5e1;
    border-radius: 4px;
}

::-webkit-scrollbar-thumb:hover {
    background: #94a3b8;
}

/* Animation utilities */
@keyframes fadeIn {
    from {
        opacity: 0;
        transform: translateY(10px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

@keyframes slideInRight {
    from {
        opacity: 0;
        transform: translateX(20px);
    }
    to {
        opacity: 1;
        transform: translateX(0);
    }
}

@keyframes pulse {
    0%, 100% {
        opacity: 1;
    }
    50% {
        opacity: 0.5;
    }
}

.animate-fadeIn {
    animation: fadeIn 0.3s ease-out;
}

.animate-slideInRight {
    animation: slideInRight 0.3s ease-out;
}

.animate-pulse {
    animation: pulse 2s cubic-bezier(0.4, 0, 0.6, 1) infinite;
}

/* Custom component styles */
.card-hover {
    transition: all 0.2s ease-in-out;
}

.card-hover:hover {
    transform: translateY(-2px);
    box-shadow: 0 10px 25px rgba(0, 0, 0, 0.1);
}

/* Risk badge animations */
.risk-badge {
    transition: all 0.2s ease-in-out;
    position: relative;
    overflow: hidden;
}

.risk-badge::before {
    content: '';
    position: absolute;
    top: 0;
    left: -100%;
    width: 100%;
    height: 100%;
    background: linear-gradient(90deg, transparent, rgba(255, 255, 255, 0.2), transparent);
    transition: left 0.5s;
}

.risk-badge:hover::before {
    left: 100%;
}

/* Chart container styles */
.chart-container {
    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);
    border-radius: 12px;
    padding: 20px;
    border: 1px solid #e2e8f0;
}

/* Loading spinner enhancement */
.loading-spinner {
    border: 3px solid #f3f4f6;
    border-top: 3px solid #8b5cf6;
    border-radius: 50%;
    width: 40px;
    height: 40px;
    animation: spin 1s linear infinite;
    margin: 0 auto;
}

@keyframes spin {
    0% { transform: rotate(0deg); }
    100% { transform: rotate(360deg); }
}

/* Navigation enhancement */
.nav-item {
    position: relative;
    transition: all 0.2s ease-in-out;
}

.nav-item::after {
    content: '';
    position: absolute;
    bottom: -2px;
    left: 50%;
    width: 0;
    height: 2px;
    background: #8b5cf6;
    transition: all 0.2s ease-in-out;
    transform: translateX(-50%);
}

.nav-item.active::after,
.nav-item:hover::after {
    width: 100%;
}

/* Protocol card enhancements */
.protocol-card {
    background: linear-gradient(135deg, #ffffff 0%, #f8fafc 100%);
    border: 1px solid #e2e8f0;
    border-radius: 12px;
    padding: 24px;
    transition: all 0.3s ease-in-out;
    position: relative;
    overflow: hidden;
}

.protocol-card::before {
    content: '';
    position: absolute;
    top: 0;
    left: 0;
    right: 0;
    height: 4px;
    background: linear-gradient(90deg, #8b5cf6, #6366f1);
    opacity: 0;
    transition: opacity 0.3s ease-in-out;
}

.protocol-card:hover::before {
    opacity: 1;
}

.protocol-card:hover {
    transform: translateY(-4px);
    box-shadow: 0 20px 40px rgba(0, 0, 0, 0.1);
    border-color: #c4b5fd;
}

/* Site card enhancements */
.site-card {
    background: #ffffff;
    border: 1px solid #e5e7eb;
    border-radius: 8px;
    padding: 20px;
    transition: all 0.2s ease-in-out;
    position: relative;
}

.site-card:hover {
    border-color: #8b5cf6;
    box-shadow: 0 8px 25px rgba(139, 92, 246, 0.1);
}

/* Capability badges */
.capability-badge {
    display: inline-flex;
    align-items: center;
    padding: 4px 8px;
    border-radius: 6px;
    font-size: 12px;
    font-weight: 500;
    transition: all 0.2s ease-in-out;
}

.capability-badge:hover {
    transform: scale(1.05);
}

/* Alert styles */
.alert {
    border-radius: 8px;
    padding: 16px;
    margin: 16px 0;
    border-left: 4px solid;
    animation: slideInRight 0.3s ease-out;
}

.alert-success {
    background-color: #f0fdf4;
    border-left-color: #22c55e;
    color: #166534;
}

.alert-warning {
    background-color: #fffbeb;
    border-left-color: #f59e0b;
    color: #92400e;
}

.alert-error {
    background-color: #fef2f2;
    border-left-color: #ef4444;
    color: #991b1b;
}

.alert-info {
    background-color: #eff6ff;
    border-left-color: #3b82f6;
    color: #1e40af;
}

/* Button enhancements */
.btn {
    position: relative;
    overflow: hidden;
    transition: all 0.2s ease-in-out;
}

.btn::before {
    content: '';
    position: absolute;
    top: 50%;
    left: 50%;
    width: 0;
    height: 0;
    border-radius: 50%;
    background: rgba(255, 255, 255, 0.3);
    transition: all 0.3s ease-out;
    transform: translate(-50%, -50%);
}

.btn:active::before {
    width: 300px;
    height: 300px;
}

.btn-primary {
    background: linear-gradient(135deg, #8b5cf6 0%, #7c3aed 100%);
    color: white;
    border: none;
    border-radius: 6px;
    padding: 8px 16px;
    font-weight: 500;
    cursor: pointer;
}

.btn-primary:hover {
    background: linear-gradient(135deg, #7c3aed 0%, #6d28d9 100%);
    transform: translateY(-1px);
    box-shadow: 0 4px 12px rgba(139, 92, 246, 0.3);
}

.btn-primary:disabled {
    opacity: 0.6;
    cursor: not-allowed;
    transform: none;
    box-shadow: none;
}

/* Table enhancements */
.table {
    width: 100%;
    border-collapse: collapse;
    background: white;
    border-radius: 8px;
    overflow: hidden;
    box-shadow: 0 1px 3px rgba(0, 0, 0, 0.1);
}

.table th {
    background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);
    padding: 12px 16px;
    text-align: left;
    font-weight: 600;
    color: #374151;
    border-bottom: 1px solid #e5e7eb;
}

.table td {
    padding: 12px 16px;
    border-bottom: 1px solid #f3f4f6;
    transition: background-color 0.2s ease-in-out;
}

.table tbody tr:hover td {
    background-color: #f8fafc;
}

/* Form enhancements */
.form-input {
    width: 100%;
    padding: 8px 12px;
    border: 1px solid #d1d5db;
    border-radius: 6px;
    font-size: 14px;
    transition: all 0.2s ease-in-out;
    background: white;
}

.form-input:focus {
    outline: none;
    border-color: #8b5cf6;
    box-shadow: 0 0 0 3px rgba(139, 92, 246, 0.1);
}

.form-select {
    width: 100%;
    padding: 8px 12px;
    border: 1px solid #d1d5db;
    border-radius: 6px;
    font-size: 14px;
    background: white;
    cursor: pointer;
    transition: all 0.2s ease-in-out;
}

.form-select:focus {
    outline: none;
    border-color: #8b5cf6;
    box-shadow: 0 0 0 3px rgba(139, 92, 246, 0.1);
}

/* Modal styles */
.modal-overlay {
    position: fixed;
    top: 0;
    left: 0;
    right: 0;
    bottom: 0;
    background: rgba(0, 0, 0, 0.5);
    display: flex;
    align-items: center;
    justify-content: center;
    z-index: 1000;
    animation: fadeIn 0.2s ease-out;
}

.modal-content {
    background: white;
    border-radius: 12px;
    padding: 24px;
    max-width: 500px;
    width: 90%;
    max-height: 80vh;
    overflow-y: auto;
    animation: slideInRight 0.3s ease-out;
}

/* Progress bar */
.progress-bar {
    width: 100%;
    height: 8px;
    background: #f3f4f6;
    border-radius: 4px;
    overflow: hidden;
}

.progress-bar-fill {
    height: 100%;
    background: linear-gradient(90deg, #8b5cf6, #6366f1);
    transition: width 0.3s ease-in-out;
}

/* Tooltip styles */
.tooltip {
    position: relative;
    cursor: help;
}

.tooltip::before {
    content: attr(data-tooltip);
    position: absolute;
    bottom: 125%;
    left: 50%;
    transform: translateX(-50%);
    background: #1f2937;
    color: white;
    padding: 8px 12px;
    border-radius: 6px;
    font-size: 12px;
    white-space: nowrap;
    opacity: 0;
    visibility: hidden;
    transition: all 0.2s ease-in-out;
    z-index: 1000;
}

.tooltip::after {
    content: '';
    position: absolute;
    bottom: 115%;
    left: 50%;
    transform: translateX(-50%);
    border: 5px solid transparent;
    border-top-color: #1f2937;
    opacity: 0;
    visibility: hidden;
    transition: all 0.2s ease-in-out;
}

.tooltip:hover::before,
.tooltip:hover::after {
    opacity: 1;
    visibility: visible;
}

/* Responsive design enhancements */
@media (max-width: 768px) {
    .protocol-card,
    .site-card {
        padding: 16px;
    }
    
    .table {
        font-size: 14px;
    }
    
    .table th,
    .table td {
        padding: 8px 12px;
    }
    
    .modal-content {
        margin: 16px;
        padding: 20px;
    }
}

/* Dark mode support (optional) */
@media (prefers-color-scheme: dark) {
    .dark-mode {
        background-color: #1f2937;
        color: #f9fafb;
    }
    
    .dark-mode .protocol-card,
    .dark-mode .site-card {
        background: #374151;
        border-color: #4b5563;
    }
    
    .dark-mode .table {
        background: #374151;
    }
    
    .dark-mode .table th {
        background: #4b5563;
        color: #f9fafb;
    }
    
    .dark-mode .form-input,
    .dark-mode .form-select {
        background: #4b5563;
        border-color: #6b7280;
        color: #f9fafb;
    }
}

/* Print styles */
@media print {
    .no-print {
        display: none !important;
    }
    
    .protocol-card,
    .site-card {
        box-shadow: none !important;
        border: 1px solid #ccc !important;
        margin-bottom: 20px;
        page-break-inside: avoid;
    }
}

/* Accessibility enhancements */
@media (prefers-reduced-motion: reduce) {
    *,
    ::before,
    ::after {
        animation-duration: 0.01ms !important;
        animation-iteration-count: 1 !important;
        transition-duration: 0.01ms !important;
    }
}

/* Focus styles for keyboard navigation */
.focusable:focus {
    outline: 2px solid #8b5cf6;
    outline-offset: 2px;
}

/* High contrast mode support */
@media (prefers-contrast: high) {
    .protocol-card,
    .site-card {
        border: 2px solid #000;
    }
    
    .btn-primary {
        background: #000;
        color: #fff;
        border: 2px solid #000;
    }
}

/* Custom utilities */
.text-gradient {
    background: linear-gradient(135deg, #8b5cf6 0%, #6366f1 100%);
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    background-clip: text;
}

.shadow-custom {
    box-shadow: 0 4px 6px -1px rgba(139, 92, 246, 0.1), 0 2px 4px -1px rgba(139, 92, 246, 0.06);
}

.border-gradient {
    border: 1px solid transparent;
    background: linear-gradient(white, white) padding-box,
                linear-gradient(135deg, #8b5cf6, #6366f1) border-box;
}

/* Performance optimizations */
.gpu-accelerated {
    transform: translateZ(0);
    will-change: transform;
}

/* Container queries support (future enhancement) */
@container (min-width: 400px) {
    .container-responsive {
        grid-template-columns: repeat(2, 1fr);
    }
}

@container (min-width: 600px) {
    .container-responsive {
        grid-template-columns: repeat(3, 1fr);
    }
}